Donald E. Knuth answers all questions

On October 5, 2001, at the Technische Universität München, Donald Knuth presented a lecture entitled "All Questions Answered". The lecture drew an audience of around 350 people, and this PDF contains the transcript,and is truely worth a read.
Originally trained as a mathematician, Donald Knuth is renowned for his research in computer science, especially the analysis of algorithms. He is a prolific author, with 160 entries in MathSciNet. Knuth is also the creator of the TEX and METAFONT languages for computer typesetting, which have revolutionized the preparation and distribution of technical documents in many fields, including mathematics.